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KMID : 0043320140370111411
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Archives of Pharmacal Research
2014 Volume.37 No. 11 p.1411 ~ p.1415
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Three new diphenylpropanes from Celastrus hindsii
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Hu Xian Qing
Han Wei
Han Zhu Zhen
Liu Qing Xin
Xu Xi Ke
Fu Peng
Li Hui Liang
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Abstract
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Three new diphenylpropanes, Hindsiipropane A?C (1?3), together with one known arylpropyl quinone Griffithane D (4), were isolated from Celastrus hindsii. Their structures were established by 1D and 2D nuclear magnetic resonance spectroscopic analysis, and mass spectroscopy. Compound 4 was firstly obtained in this genus. All the isolated compounds were evaluated in vitro for cytotoxicity against four human tumor cell lines (A549, HCT116, MDA-MB-231, BEL7404) by the MTT assay.
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KEYWORD
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Celastrus hindsii, Celastraceae, Diphenylpropanes, Arylpropyl quinone, Cytotoxicity
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